There are different feelings about this, but I checked with a local clinic and a friend that I have who is a nurse and they said that you CAN pre-fill the syringes. I have done it and I just put them in a big enough container (or cup) so I could pull one out each morning.
The opposite opinion is a NO...because it is not a glass vial and the plastic syringes aren't made for a longer storage....
Maybe you'll get some other opinions...I didn't have any problems with losing potency and it was very easy each morning to just grab it, poke and go

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Denise